منابع مشابه
Long-Term Survivors with Metastatic Uveal Melanoma
BACKGROUND To report the tumor, patient, and treatment characteristics of long-term metastatic uveal melanoma survivors. METHODS A non-comparative, retrospective case series of patients from a single institution surviving >24 months with metastatic uveal melanoma (UM). RESULTS Nine patients met the study criteria and their charts were reviewed. The mean age at diagnosis of UM was 44.1 years...
متن کاملIdentification of an Immunogenic Subset of Metastatic Uveal Melanoma.
PURPOSE Uveal melanoma is a rare melanoma variant with no effective therapies once metastases develop. Although durable cancer regression can be achieved in metastatic cutaneous melanoma with immunotherapies that augment naturally existing antitumor T-cell responses, the role of these treatments for metastatic uveal melanoma remains unclear. We sought to define the relative immunogenicity of th...
متن کاملSurvival in patients with presymptomatic diagnosis of metastatic uveal melanoma.
OBJECTIVE To determine if patients diagnosed as having metastatic uveal melanoma before the onset of symptoms experience more favorable survival outcomes than patients diagnosed after the onset of symptoms. METHODS A retrospective cohort study was performed among 90 patients who were diagnosed as having metastatic uveal melanoma after proton beam irradiation by routine surveillance testing (a...
متن کاملMetastatic uveal melanoma: diagnosis and treatment. A literature review.
In the past three decades many efforts were done to improve the visual prognosis of patients with uveal melanoma. However, mortality has remained unchanged. The systemic prognosis depends on the size and other characteristics of the lesion. It is not affected by the choice of local treatment. This suggests dissemination at an early stage. The failure to improve survival is caused by difficultie...
متن کاملIdentification of novel chemotherapeutic strategies for metastatic uveal melanoma
Melanoma of the uveal tract accounts for approximately 5% of all melanomas and represents the most common primary intraocular malignancy. Despite improvements in diagnosis and more effective local therapies for primary cancer, the rate of metastatic death has not changed in the past forty years. In the present study, we made use of bioinformatics to analyze the data obtained from three public a...
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ژورنال
عنوان ژورنال: The Cancer Journal
سال: 2012
ISSN: 1528-9117
DOI: 10.1097/ppo.0b013e31824bd256